担心、惦念

　　What's the matter? You look sad.

　　Nothing. I'm just tired.

　　What's wrong?

　　Is anything wrong?

　　What's the problem?

　　Is something bothering you?

　　Are you okay?

　　Are you all right?

　　What's going on? 到底怎么回事?

　　We were just talking.

　　What happened?

　　What's happening?

　　Is something on your mind?有什么心事吗?

　　Do you have something on your mind?

　　What are you worried about?

　　What's on your mind?

　　Is anything bothering you?

　　I was worried about you.

　　I was concerned about you.

　　I'll drop you off. 我送你回家。

　　Please don't go out of your way. 请不要特地为我而麻烦您吧

　　You look serious.

　　This is important. 这事很重要。

　　You look grave.

　　You look sad today.

　　You don't look very happy today.

　　Why are you so glum?闷闷不乐的、愁闷的

　　My girlfriend just dumped me. 抛弃

　　Why so glum? /Why the long face?

　　You look exhausted.

　　You look very tired.

　　You look worn-out.

　　It's six o'clock already.

　　Yeah, you need a break.

　　You need a rest.

　　You need to take a break.

　　You should take it easy.

　　Something is wrong with you today.

　　You're not yourself today.

　　You seem different today.

　　Who are you irritated with? *谁烦你了?

　　Who has irritated you?

　　You're nervous.

　　I think you're nervous.

　　No, I'm not nervous!

　　You seem nervous.